Sharing the costs of structural interventions: What can models tell us?

What univariate models can tell us about multivariate macroeconomic models

A longstanding feature of macroeconomic forecasting has been that a wide variety of multivariate models have struggled to out-predict univariate representations. We seek an explanation of this feature in terms of population properties. We show that if we know the univariate properties of a time-series yt these constrain tightly both the dimensions and the predictive power of the multivariate ma...

What Paint Can Tell Us

Objective: The notion that artistic capability increases with dementia is both novel and largely unsupported by available literature. Recent research has suggested an emergence of artistic capabilities to be a by-product of involuntary behaviour seen with dementia, as opposed to a progression in original thinking (de Souza, et al., 2010). A far more complementary explanation comes from Hanneman...

What can animal models tell us about human sexual response?

In all species, sexual behavior is directed by a complex interplay between steroid hormone actions in the brain that give rise to sexual arousability and experience with sexual reward that gives rise to expectations of competent sexual activity, including sexual arousal, desire, and performance. Sexual experience allows animals to form instrumental and Pavlovian associations that predict sexual...

What can proteomics tell us about platelets?

More than 130 years ago, it was recognized that platelets are key mediators of hemostasis. Nowadays, it is established that platelets participate in additional physiological processes and contribute to the genesis and progression of cardiovascular diseases. Recent data indicate that the platelet proteome, defined as the complete set of expressed proteins, comprises >5000 proteins and is highly ...

Language Use: What can it tell us?